Application submitted to : Lionel Blanchet International Chemometrics Society
PhD in Chemometrics, Radboud University Nijmegen
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At the Radboud University Nijmegen, there is a vacancy for a PhD student on the subject NMR data analysis in metabolomics The project is a cooperation of the laboratories of Pediatrics and Neurology (prof. Wevers, Radboud University Nijmegen Medical Centre) and Analytical Chemistry / Chemometrics (prof. Buydens, Institute of Molecules and Materials, Radboud University Nijmegen). Complex data are currently being measured at an ever increasing rate, to the extent that the data analysis has become the rate-limiting step. The PhD student in this project will set up and improve data analysis strategies, using chemometrics and multivariate statistics, to analyse large numbers of NMR spectra of patients with metabolic diseases. The aims of the analyses include quality control, biomarker identification, and disease classification. The candidate should have an MSc in the life sciences, chemistry, or a related discipline, with a demonstrable interest in data analysis; alternatively, candidates with a background in applied statistics, with an interest in the natural sciences, are considered as well. Knowledge of NMR and metabolomics, as well as experience in Matlab or R, are strong points. The Laboratory of Pediatrics and Neurology is a mixed function laboratory (patient care and research) of the University Medical Centre St Radboud in Nijmegen. The laboratory is specialized in genetic and metabolic disease. It uses proton NMR spectroscopy of body fluids to find a diagnosis in children with metabolic disorders and applies a metabolomics strategy to find biomarkers for specific diseases and to unravel their etiological background. The Department of Analytical Chemistry / Chemometrics specializes in multivariate data analysis spectroscopic and chromatographic data. It is involved in several national and international research projects, both with academia and industry. More information about the department can be found at http://www.ru.nl/science/analyticalchemistry/
Internet link : Department of Analytical Chemistry / Chemometrics
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